Civitavecchia (Rome) to Piraeus (Athens)

All roads lead to Rome, and with good reason - this city is one of the world’s most thrilling, offering unmatched history along every street. An evocative, inspiring and utterly artistic capital of unrivalled cultural impact, Rome is a city of back-to-back landmarks, which will take you on an exhilarating journey through the ages. This may be one of the world’s oldest cities, but it’s well and truly lived in. The ruins are punctuated with murmuring cafes, and the outdoor seating of restaurants sprawls out across piazzas, enticing you to sample tangles of creamy pasta and crispy pizzas. Rome’s incredible Roman Forum is littered with the ruins of its ancient administrations, which have stood firm for 2,000 years, since the times when the area was the centre of the Western world. Few sites are more simultaneously beautiful and haunting than that of the storied Colosseum, which looms deep into Rome’s rich blue sky. Take a tour to learn details of the grisly goings-on within. The best way to experience Rome is to wander its streets, gelato in hand. There is a lot to see here - whether it’s the domed spectacle of the Pantheon, or the elaborate flowing waters and artistry of the Trevi Fountain. Vatican City is an astonishing, colossal display of Catholic grandeur, while the Spanish Steps – crowned by the Trinità dei Monti church – offer a beautiful spot to gather and soak up the lively atmosphere of this humming city. With so much on the to-do list, you’ll relish the breaks you take, enjoying simple pleasures like a strong espresso, or fresh pasta with tomato sauce and ripped basil.

Set high atop the Mediterranean cliffs, Sorrento is a town of extraordinary beauty that has endured as a favoured resort for centuries. In addition to its own attractions, Sorrento is also known as a popular gateway to Pompeii, Italy's most celebrated classical ruins. They offer a look at the finest example of a Roman town and its way of life, presented to modern eyes by excavation. The ever-popular Isle of Capri is just a short distance from Sorrento by jet-foil. It ranks as one of Italy's most beautiful islands and has captured the fancy of visitors for centuries. Its excellent year-round climate, spectacular landscape and fantastic sea caverns ensure a never-ending stream of tourists. In addition, the island boasts lavish villas, elegant hotels, chic boutiques and quaint restaurants, making it easy to understand why Capri has become so popular. Discover the charm of Sorrento, enjoy the famous archaeological sites and breathtaking scenery of the Amalfi Drive, or sit in a shady sidewalk café with an espresso or a cold drink and savour the local ambiance.

Hugging a long, sweeping bay, Giardini Naxos welcomes you ashore to some of Sicily’s most scenic and historic sites. Naxos was the first Greek settlement on Sicily, and it is surrounded by remarkable remains and swirling mythology. With a long arc of sun-soaked golden sand, you can kick back by the waves - and cool off with a dip into the sea's refreshing embrace. Up above the seaside revelry, the spectacular Taormina hillside town perches - containing rich Roman and Greek history. View less Visit to encounter one of Sicily’s best views, as you look down over the rejuvenating blue of the sea, and the looming backdrop of Mount Etna rising in the distance. The majestic, honey-coloured Greek theatre is a highlight, standing before the distant loom of the volcano. Head towards the puffs of cloud, and wisps of smoke, that gather around the peak of Sicily’s mighty volcano, which is among the most active in Europe. Arrive through vineyards, thriving in this fertile soil, before taking the 1,737-metre incline to the summit of the legendary mountain of fire, across fields of solidified lava flows. Known to the Greeks as the home of the God of Fire, and the one-eyed Cyclops, the mountain continues to amaze and awe with its restless power. Vineyards carpet the scenery - interrupted by occasional cactai and citrus groves – and produce some of Sicily’s most refined flavors. Enjoy a glass of wine on Giardini Naxos’ seafront, and toast your time on these rich Sicilian shores.

The island of Mykonos is the most easterly of the northern Cyclades. Its attractive setting and other captivating attributes make it one of the most celebrated holiday destinations in Greece. Mykonos Town is a colorful maze of narrow streets lined by whitewashed houses with bright blue doors and shutters. During the 1960s, it was the Bohemian jet set that discovered Mykonos. Many old houses along the waterfront are now restaurants, bars and discos, catering to an international yachting crowd. The tiny town of cube-shaped houses extends in a semicircle around the picturesque bay. As an attractive backdrop, the famous windmills are lined up like toy soldiers on the hillside, vestiges of a time when wind power was used to grind the island's grain.

Volos is a commercial and industrial city; it is Greece's third-largest port. Much of it has been rebuilt after a severe earthquake in 1955. The location in the gulf of the same name and near scenic Mount Pelion ensures this town an attractive setting. Interesting sites in the surrounding areas include imposing monasteries perched atop craggy mountains and a fine Archaeological Museum. Volos was founded in the 14th century in an area which has been occupied by man since the Neolithic era. A short distance out of Volos, the second millennium saw the establishment of the Mycenaen city of Iolkos, seat of King Pelias and home of his nephew Jason, who sailed from here with the Argonauts. Remains of Mycenaen buildings have been discovered near the river, where a palace stood around 1400 B.C. The main reason visitors come to Volos is to depart on excursions to the monasteries of Meteora. Their lofty position atop gigantic pinnacles makes them the area's foremost attraction.

It is interesting to note that between the 17th and 20th centuries Jews made up more than half the population as a result of the arrival in 1492 of some 20,000 Jews who had been expelled from Spain. They engaged in all trades and professions and played a predominant part in commerce and industry. Thessaloniki's main hub centers around Aristotle Square, a traffic- free area surrounded by arcades that house cafes and restaurants. The pedestrian strip along the water's edge makes for a popular seafront promenade. Two of the main thoroughfares, Odos Mitropoleos and Odos Tsimski, are lined with luxury shops and boutiques. On either side of Aristotle Street extends the picturesque Central Market where you will find numerous shops supplying domestic needs

A chaotic, colossal collision of east and west – start your day in Europe and end it in Asia, all without breaking a sweat. Sprawling across two continents, the city has been toed, froed and yanked between countless civilisations over its history, leaving a multi-layered, majestic tapestry of culture to untangle. An army of narrow minarets puncture the skyline, while the soaring towers of palaces and labyrinths of bazaars - where bargains are the reward for brave hagglers - fill up this dynamic city of 15 million people. View less With a rich portfolio of Byzantine and Ottoman architecture, Istanbul enjoys one of the world's most dynamic skylines and has an intense, infectious energy. The vast Aya Sofya is the starting point for exploring this huge city's deep wealth of cultural treasures. Built in the 6th century as a Greek Orthodox church, it was later transformed into an Ottoman imperial mosque – and latterly a museum. Cast your eyes up to take in the full scale of the colossal dome, one of the world's largest, which floats on a magnificent bed of light. See the Blue Mosque, with its glorious blue İznik tiles, or head to the Galata Tower which was once the tallest structure in Istanbul, and is ideal for a panoramic view of the city. Grab handfuls of dates and spices, shop for jewellery and patterned fabrics as you're swallowed whole by the Grand Bazaar - one of the world's biggest and busiest covered indoor markets. To understand Istanbul is to visit its kahvehans. Few rituals are taken as seriously as Turkish coffee - prepared to be incredibly strong. Sweeten the aftertaste with Turkish delight, or baklava – try the smooth pistachio version called kuru baklava.

A chaotic, colossal collision of east and west – start your day in Europe and end it in Asia, all without breaking a sweat. Sprawling across two continents, the city has been toed, froed and yanked between countless civilisations over its history, leaving a multi-layered, majestic tapestry of culture to untangle. An army of narrow minarets puncture the skyline, while the soaring towers of palaces and labyrinths of bazaars - where bargains are the reward for brave hagglers - fill up this dynamic city of 15 million people. View less With a rich portfolio of Byzantine and Ottoman architecture, Istanbul enjoys one of the world's most dynamic skylines and has an intense, infectious energy. The vast Aya Sofya is the starting point for exploring this huge city's deep wealth of cultural treasures. Built in the 6th century as a Greek Orthodox church, it was later transformed into an Ottoman imperial mosque – and latterly a museum. Cast your eyes up to take in the full scale of the colossal dome, one of the world's largest, which floats on a magnificent bed of light. See the Blue Mosque, with its glorious blue İznik tiles, or head to the Galata Tower which was once the tallest structure in Istanbul, and is ideal for a panoramic view of the city. Grab handfuls of dates and spices, shop for jewellery and patterned fabrics as you're swallowed whole by the Grand Bazaar - one of the world's biggest and busiest covered indoor markets. To understand Istanbul is to visit its kahvehans. Few rituals are taken as seriously as Turkish coffee - prepared to be incredibly strong. Sweeten the aftertaste with Turkish delight, or baklava – try the smooth pistachio version called kuru baklava.

Çeşme is a Turkish resort town west of Izmir, on the Aegean Sea. Overlooking the harbor is Çeşme Castle, a restored military fortress. It now houses the Çeşme Archaeology Museum, with displays of marble busts, metal coins and artifacts from nearby excavations. On the east side of the Çeşme peninsula is sandy Ilica Beach, with warm thermal sulfur springs. Around Çeşme are clear waters and accessible dive sites

The former capital of Greece is a popular town on the eastern coast of the Peloponnese. Stately, medieval architecture recalls its Venetian occupation in the 15th century. The most dominant structure from this time is the crenellated Palamidi Fortress towering high above the town. The lively port and resort town spreads around a scenic harbor. Its center is crisscrossed by narrow streets, which are best negotiated on foot. Several monuments remain from the towns' Turkish past, including a mosque and the parliament building. Relics from ancient sites are on display in the Archaeological Museum. Those who are interested in handicrafts and traditional costumes may enjoy a visit to the Folk Art Museum. Enjoy exploring along the waterfront and around the main square of the Old Town. Open-air cafés and restaurants invite you for a break to enjoy a light snack or a seafood lunch while taking in the local atmosphere.