Civitavecchia (Rome) to Piraeus (Athens)

All roads lead to Rome, and with good reason - this city is one of the world’s most thrilling, offering unmatched history along every street. An evocative, inspiring and utterly artistic capital of unrivalled cultural impact, Rome is a city of back-to-back landmarks, which will take you on an exhilarating journey through the ages. This may be one of the world’s oldest cities, but it’s well and truly lived in. The ruins are punctuated with murmuring cafes, and the outdoor seating of restaurants sprawls out across piazzas, enticing you to sample tangles of creamy pasta and crispy pizzas. Rome’s incredible Roman Forum is littered with the ruins of its ancient administrations, which have stood firm for 2,000 years, since the times when the area was the centre of the Western world. Few sites are more simultaneously beautiful and haunting than that of the storied Colosseum, which looms deep into Rome’s rich blue sky. Take a tour to learn details of the grisly goings-on within. The best way to experience Rome is to wander its streets, gelato in hand. There is a lot to see here - whether it’s the domed spectacle of the Pantheon, or the elaborate flowing waters and artistry of the Trevi Fountain. Vatican City is an astonishing, colossal display of Catholic grandeur, while the Spanish Steps – crowned by the Trinità dei Monti church – offer a beautiful spot to gather and soak up the lively atmosphere of this humming city. With so much on the to-do list, you’ll relish the breaks you take, enjoying simple pleasures like a strong espresso, or fresh pasta with tomato sauce and ripped basil.

Honey-coloured Siracusa is a staggering UNESCO World Heritage Site, and an extraordinary Sicilian city of immense ancient history. The modern population is a fraction of what it was at the city’s heyday around 400 BC, when Athens’ might was successfully challenged and faced down, reinforcing the city’s incredible power and status. Siracusa’s historical nucleus waits to be discovered on the compact islet of Ortygia. The city was founded here, but grew over time, spreading across to the mainland. View less A small channel separates the two, which is now spanned by twin bridges. Wander the atmospheric streets of this time warp, to reach the shining elegance of Piazza Duomo. The Baroque cathedral rises like a giant sandcastle, and you can settle opposite to cradle a glass of wine and enjoy the view over the immaculate square - people watching before the glorious baroque façade. Dig deep into its history at the mainland's archaeological park. Here you can wander between the remains of a Greek theatre, constructed in the 5th century BC, and now used as a grandiose, atmospheric venue for events and performances. You’ll also encounter a Roman Amphitheatre - where gladiators battled brutally, and the spectacular ear-shaped cave, which is famed for its extraordinary, secret-revealing acoustics. It was given its name - the Ear of Dionysius - by Caravaggio. Visit the legendary Fonte Arethusa, or lose yourself in the Ortygia Market – you’ll find everything here, from fresh fish, to spices and local bottles of wines. Look out for a flavour-filled jar of real Sicilian u strattu - an intense tomato paste that is the secret ingredient to many Sicilian recipes. The local ingredients are imbued with flavour by this volcanic land’s fertile soils and the firepower of Europe’s most active volcano Mount Etna, waits just to the north.

Perched high on the imposing Sciberras Peninsula, Valletta immediately presents its massive, protective walls and vertical bastions to visitors arriving by sea. Rising to 47 metres in places, the fortifications protect lavish palaces, grand domes and illustrious gardens. Built by the Knights of St John on the narrow peninsular, Valletta is a compact, richly historical treasure trove of Baroque wonders. Ascend to reach the restful, flower-filled Upper Barrakka Gardens, where cannons fire and boom in salute at noon each day, sending echoing cracks of noise out across the waves below. View less Recognised as 2018’s European Capital of Culture, Valletta is a fascinating and dense haven of history and intrigue. A busy, bustling capital, the breathtaking St John’s Cathedral - commissioned in 1572 - is almost concealed among its narrow streets. The relatively modest exterior is counterpointed by a staggeringly opulent, gold-leaf bathed interior, containing a Caravaggio masterpiece - the shadowy vision of the Beheading of St John. Cinematic and magnificent, Valletta has served as a filming location for Game of Thrones - but real epic history abounds on this rocky isle too. From the prehistoric and megalithic sites of the Hypogeum of Paola and Tarxien, to the fascinating War Museum at Fort St Elmo. Mdina also waits nearby, and the former medieval capital is a striking contrast to the island’s main city. Cars are barred from its streets, and it offers endlessly atmospheric old-time wanders. With a strategic positioning in the Mediterranean, Malta is a jewel that many have wrestled for over the centuries. Independence from Britain was finally achieved in 1964, but the close allegiance remains evident, with English recognised as an official language, cars driving on the left, and red post boxes and telephone gleaming in Malta’s sunshine.

The tiny port of Katakolon serves primarily as the starting point for an excursion to the archaeological site of ancient Olympia. Adjacent to the port is the small village of Katakolon with a few souvenir shops and typical local restaurants. Ancient Olympia, the great Panhellenic sanctuary, is located 21 miles from the port. The site of ancient Olympia spreads out at the foot of wooded Mount Kronos. Excavations began in 1875; they are considered one of archaeology's great achievements. A direct consequence was the revival of the Olympic Games by Baron Pierre de Coubertin. Today's visitors walk among the ruins and reflect on their significance. Don't miss the site where the Olympic flame is lit even today for the modern games.

Milos or Melos is a volcanic Greek island in the Aegean Sea, just north of the Sea of Crete. Milos is the southwesternmost island in the Cyclades group. The Venus de Milo and the Asclepius of Milos were both found on the island, as were a Poseidon and an archaic Apollo now in Athens.

The Holy Isle of Patmos, one of the smaller Dodecanese Islands, occupies a narrow strip of land with numerous rocky hills and scant vegetation. The interior is sparsely populated with mostly shepherds and fishermen. In contrast, the waterfront areas see plenty of tourists during the summer months. There are only two main villages, Chora and Scala; whitewashed houses face Scala harbor or are scattered over the hillsides. The island's mild, healthy climate, year-round sunshine, delightful coves and numerous chapels combine to form a picture of unique beauty. The history of Patmos can be traced to Dorian and Ionian settlers who established a sanctuary to worship the goddess Artemis.