Civitavecchia (Rome) to Piraeus (Athens)

All roads lead to Rome, and with good reason - this city is one of the world’s most thrilling, offering unmatched history along every street. An evocative, inspiring and utterly artistic capital of unrivalled cultural impact, Rome is a city of back-to-back landmarks, which will take you on an exhilarating journey through the ages. This may be one of the world’s oldest cities, but it’s well and truly lived in. The ruins are punctuated with murmuring cafes, and the outdoor seating of restaurants sprawls out across piazzas, enticing you to sample tangles of creamy pasta and crispy pizzas. Rome’s incredible Roman Forum is littered with the ruins of its ancient administrations, which have stood firm for 2,000 years, since the times when the area was the centre of the Western world. Few sites are more simultaneously beautiful and haunting than that of the storied Colosseum, which looms deep into Rome’s rich blue sky. Take a tour to learn details of the grisly goings-on within. The best way to experience Rome is to wander its streets, gelato in hand. There is a lot to see here - whether it’s the domed spectacle of the Pantheon, or the elaborate flowing waters and artistry of the Trevi Fountain. Vatican City is an astonishing, colossal display of Catholic grandeur, while the Spanish Steps – crowned by the Trinità dei Monti church – offer a beautiful spot to gather and soak up the lively atmosphere of this humming city. With so much on the to-do list, you’ll relish the breaks you take, enjoying simple pleasures like a strong espresso, or fresh pasta with tomato sauce and ripped basil.

The region of Campania was home to Greeks settlers some 300 years before Rome was founded. Pompeii, too, was a Greek town before being conquered by the Romans during the 5th century BC. It was under the Romans that Pompeii flourished and grew prosperous. When Mount Vesuvius erupted in 79 AD, the population of 20,000 was wiped out, but dozens of buildings were preserved under layers of cinder more than 20 feet deep. The most important finds from Pompeii are displayed in Naples' National Archaeological Museum. A visit here will no doubt enhance a visit to ancient Pompeii.

The tiny port of Katakolon serves primarily as the starting point for an excursion to the archaeological site of ancient Olympia. Adjacent to the port is the small village of Katakolon with a few souvenir shops and typical local restaurants. Ancient Olympia, the great Panhellenic sanctuary, is located 21 miles from the port. The site of ancient Olympia spreads out at the foot of wooded Mount Kronos. Excavations began in 1875; they are considered one of archaeology's great achievements. A direct consequence was the revival of the Olympic Games by Baron Pierre de Coubertin. Today's visitors walk among the ruins and reflect on their significance. Don't miss the site where the Olympic flame is lit even today for the modern games.

A chaotic, colossal collision of east and west – start your day in Europe and end it in Asia, all without breaking a sweat. Sprawling across two continents, the city has been toed, froed and yanked between countless civilisations over its history, leaving a multi-layered, majestic tapestry of culture to untangle. An army of narrow minarets puncture the skyline, while the soaring towers of palaces and labyrinths of bazaars - where bargains are the reward for brave hagglers - fill up this dynamic city of 15 million people. View less With a rich portfolio of Byzantine and Ottoman architecture, Istanbul enjoys one of the world's most dynamic skylines and has an intense, infectious energy. The vast Aya Sofya is the starting point for exploring this huge city's deep wealth of cultural treasures. Built in the 6th century as a Greek Orthodox church, it was later transformed into an Ottoman imperial mosque – and latterly a museum. Cast your eyes up to take in the full scale of the colossal dome, one of the world's largest, which floats on a magnificent bed of light. See the Blue Mosque, with its glorious blue İznik tiles, or head to the Galata Tower which was once the tallest structure in Istanbul, and is ideal for a panoramic view of the city. Grab handfuls of dates and spices, shop for jewellery and patterned fabrics as you're swallowed whole by the Grand Bazaar - one of the world's biggest and busiest covered indoor markets. To understand Istanbul is to visit its kahvehans. Few rituals are taken as seriously as Turkish coffee - prepared to be incredibly strong. Sweeten the aftertaste with Turkish delight, or baklava – try the smooth pistachio version called kuru baklava.

A chaotic, colossal collision of east and west – start your day in Europe and end it in Asia, all without breaking a sweat. Sprawling across two continents, the city has been toed, froed and yanked between countless civilisations over its history, leaving a multi-layered, majestic tapestry of culture to untangle. An army of narrow minarets puncture the skyline, while the soaring towers of palaces and labyrinths of bazaars - where bargains are the reward for brave hagglers - fill up this dynamic city of 15 million people. View less With a rich portfolio of Byzantine and Ottoman architecture, Istanbul enjoys one of the world's most dynamic skylines and has an intense, infectious energy. The vast Aya Sofya is the starting point for exploring this huge city's deep wealth of cultural treasures. Built in the 6th century as a Greek Orthodox church, it was later transformed into an Ottoman imperial mosque – and latterly a museum. Cast your eyes up to take in the full scale of the colossal dome, one of the world's largest, which floats on a magnificent bed of light. See the Blue Mosque, with its glorious blue İznik tiles, or head to the Galata Tower which was once the tallest structure in Istanbul, and is ideal for a panoramic view of the city. Grab handfuls of dates and spices, shop for jewellery and patterned fabrics as you're swallowed whole by the Grand Bazaar - one of the world's biggest and busiest covered indoor markets. To understand Istanbul is to visit its kahvehans. Few rituals are taken as seriously as Turkish coffee - prepared to be incredibly strong. Sweeten the aftertaste with Turkish delight, or baklava – try the smooth pistachio version called kuru baklava.

Canakkale is the main city of the province of the same name situated on both sides of the Dardanelles and with its shores touching both Europe and Asia Minor. The city has been strategically significant for millennia as a crossover point of migrants, traders and armies. Today, colourful yachts pass through the strait and stop at Canakkale to visit this historically rich area, home to many widely known legends.

Since the late 1970s, Kusadasi has grown from a fishing village into a sprawling tourist center, serving thousands of visitors who flock here to visit the nearby ruins of Ephesus. Despite an incredible building boom and an influx of shops, Kusadasi has managed to retain much of its original charm. The major attraction remains the archaeological site of ancient Ephesus, considered to be the most important one in all of Turkey. The history of this ancient city dates as far back as the 10th century BC. Many of the remarkable structures seen today are the result of an extraordinary excavation and restoration program. As you walk along the white marble road, grooved by ancient chariot wheels, the two-story Library of Celsus presents a striking sight. In addition, there are temples, houses of noblemen and community buildings lining the ancient streets. Nestled into the mountainside is the 25,000-seat amphitheater, still used today for performances during the Festival of Culture and Art.

The island of Mykonos is the most easterly of the northern Cyclades. Its attractive setting and other captivating attributes make it one of the most celebrated holiday destinations in Greece. Mykonos Town is a colorful maze of narrow streets lined by whitewashed houses with bright blue doors and shutters. During the 1960s, it was the Bohemian jet set that discovered Mykonos. Many old houses along the waterfront are now restaurants, bars and discos, catering to an international yachting crowd. The tiny town of cube-shaped houses extends in a semicircle around the picturesque bay. As an attractive backdrop, the famous windmills are lined up like toy soldiers on the hillside, vestiges of a time when wind power was used to grind the island's grain.

The former capital of Greece is a popular town on the eastern coast of the Peloponnese. Stately, medieval architecture recalls its Venetian occupation in the 15th century. The most dominant structure from this time is the crenellated Palamidi Fortress towering high above the town. The lively port and resort town spreads around a scenic harbor. Its center is crisscrossed by narrow streets, which are best negotiated on foot. Several monuments remain from the towns' Turkish past, including a mosque and the parliament building. Relics from ancient sites are on display in the Archaeological Museum. Those who are interested in handicrafts and traditional costumes may enjoy a visit to the Folk Art Museum. Enjoy exploring along the waterfront and around the main square of the Old Town. Open-air cafés and restaurants invite you for a break to enjoy a light snack or a seafood lunch while taking in the local atmosphere.